Exploring the Use of Medical Marijuana for Supportive Care of Oncology Patients.

Medical marijuana, also known as cannabis, is being sought by patients and survivors to alleviate common symptoms of cancer and its treatments that affect their quality of life. The National Academy of Sciences (2017) reports conclusive or substantial evidence that cannabis is successful in treating chronic cancer pain and chemotherapy-induced nausea and vomiting, moderate evidence that cannabinoids are beneficial for sleep disorders that accompany chronic illnesses, and limited evidence supporting use for appetite stimulation and anxiety. However, due to the fact that cannabis is classified as a Schedule I controlled substance, there is an absence of rigorous, scientific evidence to guide health-care professionals. In addition, the Schedule I designation makes it illegal for health-care professionals in the United States to prescribe, administer, or directly distribute these drugs. Legislation has outpaced research in this area. Therefore, the National Council of State Boards of Nursing (NCSBN) appointed a medical marijuana guideline committee to create guidelines for the nursing care of patients using medical marijuana, marijuana education in nursing programs, and guidelines for advanced practice registered nurses (APRNs) certifying a patient for the use of medical marijuana (The NCSBN Medical Marijuana Guidelines Committee, 2018). Six states/districts authorize APRNs to recommend the use of medical marijuana to patients with qualifying conditions (Kaplan, 2015). As of March 2021, 35 states plus the District of Columbia have authorized the use of medical marijuana (DISA Global Solutions, 2021). Therefore, APRNs will be caring for these patients and need to know the medical, pharmacological, and legal issues surrounding medical cannabis use.

Lactic acidosis in patients with cancer.

Lactic acidosis is the most common metabolic acidosis in hospitalized patients-the result from an underlying pathogenic process. To successfully manage lactic acid production, its cause needs to be eliminated. Patients with cancer have many risk factors for developing lactic acidosis, including the cancer diagnosis itself. Patients with lactic acidosis are critically ill, requiring an intense level of nursing care with accompanying frequent cardiopulmonary and renal assessments. The mortality rate from lactic acidosis is high. Therefore, appropriate nursing interventions may include end-of-life and palliative care.

Care of the open abdomen after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies.

A patient with a mucinous appendiceal cancer presents to the surgeon complaining of abdominal discomfort and nausea. Having undergone a prior right hemicolectomy, the patient has been disease free and on surveillance with clinical and carcinogenic antigen (CEA) monitoring. The CEA was noted to be elevated and a computed tomography scan revealed peritoneal nodules throughout the abdomen with a presumptive diagnosis of pseudomyxoma peritonei (progressive peritoneal implants from a mucinous primary). Several therapeutic options were offered and the patient selected to undergo cytoreductive surgery (CRS) with the potential to receive hyperthermic interoperative chemotherapy (HIPEC). Extensive resection was performed, including removal of the entire greater omentum, partial gastrectomy, and total pelvic exenteration with end colostomy and ileal conduit. Reassessment of the peritoneal cavity after the resections revealed almost complete cytoreduction. HIPEC was performed with mitomycin C and, after drainage and abdominal washing, the intestinal segments were anastomosed and the abdominal wall closed. Seven days postoperatively, an acute abdomen with septic shock developed as a result of a leak from the ileocolonic anastomosis. The patient returned to the operating room and an exploratory laparotomy, a small bowel resection, a resection of the ileocolonic anastomosis, and an abdominal washout were performed. Edema of the bowel caused by peritonitis resulting from the anastomotic leak necessitated delayed closure of the abdominal wall. A temporary abdominal closure using the ABThera™ Open Abdomen Negative Pressure Therapy system was applied and the abdomen was eventually closed.

Recovery after transverse rectus abdominis myocutaneous flap breast reconstruction surgery.

PURPOSE/OBJECTIVES: To assess pain and activity limitations and to determine realistic goals for recovery after a transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction in a standard rehabilitation and recovery program. Assessing patient satisfaction with educational information is a secondary objective. DESIGN: Before and after comparison. SETTING: A National Cancer Institute--designated comprehensive cancer center in the mid-Atlantic United States. SAMPLE: 16 women who had TRAM flap breast reconstruction. METHODS: Data were collected before surgery and four and eight weeks after surgery using an adapted Brief Pain Inventory, a recovery and rehabilitation assessment, and an evaluation of patient satisfaction. MAIN RESEARCH VARIABLES: Presence of pain; disruption of activities, relationships, and mood because of pain; pain relief measures; active range of motion; muscle strength; and satisfaction with educational information. FINDINGS: Pain and activity limitation scores were elevated four weeks after surgery and returned almost to baseline at eight weeks. Abdominal pain was significantly higher for women with free versus pedicled TRAM flap surgery, and women with previous back pain reported more lower back pain after surgery. Opioids, followed by nonsteroidal antiinflammatory drugs, were the most common pain relief method. Active range of motion and muscle strength showed no significant limitations at eight weeks. Patients were very satisfied with the educational information provided by nurses and physical therapists. CONCLUSIONS: Women can expect to have some pain and activity limitations four weeks after surgery but will be almost fully recovered at eight weeks. Educational information on pain management and resuming an active lifestyle were useful. IMPLICATIONS FOR NURSING: Nurses and physical therapists can positively influence recovery from TRAM flap breast reconstruction by educating patients.

Getting the point about fibromyalgia.

Invisible and incurable, this disorder can wreak havoc with your patient's life. Find out how to get her back on track. Fibromyalgia, a complex, chronic disorder of pain processing, is thought to be the most common cause of generalized musculoskeletal pain in women ages 20 to 55. This disorder, which affects the muscles, ligaments, and tendons, occurs in 3 to 6 million Americans, mostly women. Some patients are affected only mildly, but up to 30% have symptoms that seriously impair their quality of life.

Spread the word about breast cancer.

Whether you're teaching patients about maintaining health or treatment options, be sure to share the latest information about breast cancer.

Cachexia in patients with advanced cancer.

Cancer cachexia generally is considered to be the end stage in the progression of nutritional deterioration and wasting of malignancy (Ottery, 1995). In patients with advanced cancer, this condition is very common and decreases quality of life, as well as survival (Fearon et al., 2001; Ottery; Smith & Souba, 2001; Whitman, 2000). However, if early diagnosis and intervention can control cachexia, the potential exists to greatly improve a patient's quality of life and prolong survival. Because metabolic alterations inhibit the effective use of conventional nutritional support, anti-inflammatory agents or fish oil are possible options. Orexigenic agents may be prescribed if patients wish to improve oral intake. Steroids and progestational agents may be used to attempt to improve mood and appetite. Nutrition affects symptoms that need to be managed effectively. Nurses should work aggressively to correct factors that contribute to decreased food intake (e.g., nausea, pain) and correct factors that worsen debility (e.g., anemia). Information must be presented so that informed choices can be made and realistic eating goals set. An interdisciplinary approach that involves the nurse, physician, dietician, and possibly social worker or case manager, as well as the patient and family, is necessary to identify nutritional alterations, assess specific needs, and plan individual interventions. Whitman (2000) stated that counseling is the most effective and least expensive intervention. It may be conducted by any member of the healthcare team and should be combined with other interventions. Palliation of cachexia in patients with advanced cancer is a challenge for nurses. Hopefully, early and judicious use of these interventions may decrease the significant morbidity and mortality that result from cancer cachexia.

Deep vein thrombosis in the patient with cancer.

The association between thromboembolic disease and cancer has long been recognized. Armand Trousseau first brought this association to the attention of the medical profession in 1868 (Haire, 2000). Oncology nurses need to be knowledgeable about preventive measures, early signs and symptoms of thromboembolic disease, and complications of therapy.